Many investigations exist on the searching of markers to distinguish lymphocyte populations to enlarge knowledge about immunereaction and also of appropriate markers for breeding programms. The most investigations deal with lymphocyte surface markers. The pattern of rRNA-synthesis in the nucleus visible with silverstaining technique could be a good completion to the other markers. In this investigation an analysis of this pattern to distinguish between functional or cellcycle pattern and genetical fixed structures was done by the aid of a modell. In this standardized mouse infection model1, infected with Listeria monocytogenes, it is possible to read off the immune status of the mice at any time. Thus conclusions could be drawn concerning the functional status of the cells respectively of the rRNA-pattern in the nuclei.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 7. Symposia (1), , 117-120, 1982
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