Abstract

Divergent selection was conducted over eight generations in mice for one of two criteria: epididymal fat pad weight or hind carcass weight, each taken as a percentage of body weight. Two replicate lines were designated for each selection treatment including randomly selected controls. Selection within full sib families was based on performance of 12-week-old males after they had sired a litter. Realized heritabilities were estimated from the regression of response on cumulative selection differential. Responses were corrected for environmental effects by two methods. Method 1 used generation means from all lines and method 2 used deviations of selected from control line means. Realized heritabilities, adjusted to an individual basis and pooled across replicates, were as follows (method 1, method 2): for epididymal fat pad percent, high, 0.58 + 0.06, 0.60 + 0.09; low, 0.76 + 0.08, 0.83 + 0.23; for hind carcass percent, high 0.46 + 0.05, 0.53 + 0.04; low, 0.34 + 0.20, 0.28 + 0.21. Realized genetic correlation between epididymal fat pad percent and hind carcass percent was similar for different methods of estimation and showed no evidence of asymmetry; pooled estimates were -0.65 + 0.13 from high lines and -0.75 + 20 from low lines.
 

E. J Eisen

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XI. Genetics of reproduction, lactation, growth, adaptation, disease, and parasite resistance., , 389–394, 1986
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