Abstract

Transfer of extra copies of the gene for growth hormone into the genome of mice and pigs has been shown to increase growth performance (Owens et al. 1989; Vize et al. 1988). An important step in the integration of transgenes into a breeding programme is the determination of their effect on phenotypic and genetic parameters. Transgenic mice provide a useful model for these investigations. This study was designed to evaluate the effect of a porcine growth hormone (pGH) transgene on some genetic and phenotypic parameters for growth and reproduction traits in mice. Preliminary results are presented. 

J. L Wilkinson, B. G Luxford

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XIII. Plenary lectures, molecular genetics and mapping, selection, prediction and estimation., , 333–336, 1990