Instead o f making a complete summary o f all the papers of this session, the moderator will make a general introduction or overview and restrict his comments on the papers for two main reasons: 1) Delay in receiving the manuscripts expected and changes in the list of speakers due to renouncements and replacements. 2) The workshop papers cover necessarily a restricted part of this comprehensive field.
There are two major issues connected with the subject "genetics of disease resistance" in the context of livestock production. Firstly the basic issue: How to identify the genetic basis or the genes behind disease resistance or susceptibility and possibly to identify the actual causative mechanisms involved. Secondly, the applied issue: How to employ the acquired knowledge in breeding strategies to improve genetic resistance in livestock. A lot of research has been and is still being carried out specifically aimed to answer the above questions. This is clearly reflected in the present workshop. Also research projects with objects different from the present one provide spin off knowledge for understanding the genetics of disease resistance. Examples of such projects are gene mapping programmes, studies on: defence molecules and defence mechanisms, pathogenesis, regulation of gene expression together with transgenic experiments, and last but not least molecular modelling and protein engineering, creating new genes and new gene products with novel properties.
The concept "disease resistance” within the framework of this workshop embraces resistance or susceptibility to infections, parasite invasions included. Non infectious diseases and disorders arc not included for the reason of space and time.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XVI. Poultry, fish and horse genetics and breeding, growth and reproduction, immune response and disease resistance., , 421–426, 1990
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