Contribution of growth hormone (GH), insulin-like growth factor-1 (IGF-1), and linked loci to growth and carcass traits in offspring of purebred sires was examined through segregation analysis. Offspring (n=150, 195 and 148) from three sires were genotyped at the GH and IGF-1 loci and evaluated for preweaning and postweaning average daily gain, 10th rib backfat and loin-eye area. Paternal GH and IGF-1 marker inheritance was determined and their association with growth and carcass traits evaluated. Significant associations were observed between GH genotype and loin-eye area in one family and between IGF-1 genotype and postweaning average daily gain in two families. The results of this study suggest the possibility of an association between GH and IGF-1 and growth and carcass traits. Additional studies of a more comprehensive genomic scope are planned.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 272–275, 1994
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