Recently we developed a new statistical method for mapping quantitative trait loci (QTLs). Compared to current QTL mapping methods, our method has a number of advantages and can more accurately and efficiently locate multiple QTLs. The method is based on a procedure which combines the interval mapping with an interval test. Theoretically, this method is more complex and versatile than the current methods and allows a host of models be fitted in data to explore fully the complex information in a data set. We have now implemented the method for several commonly used experimental designs and for multiple trait analysis.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 37–40, 1994
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