The Dairy Bull DNA Repository (DBDR) was established in 1992 as a DNA resource for mapping quantitative trait loci (QTL) associated with milk production, composition and health traits. Currently, the core of the DBDR consists of 16 grandsire families. The 16 core grandsire families have 40 or more sons per grandsire with a total of 1513 sons and at least 527,846 grand-daughters. For a marker with five alleles and equal allele frequency, on average we expea 970 informative sons with 338,407 daughter records for the detection of QTL. Frequency of heterozygous grandsires for 31 markers ranged from 11% to 100%. Prediaed frequency of informative sons averaging over heterozygous grandsires was in the range of .5 to .84.

Y. Da, M. Ron, A. Yanai, M. Band, R. E Everts, D. W Heyen, J. I Weller, G. R Wiggans, H. A Lewin

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 229–232, 1994
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