A derivative-free Residual Maximum Likelihood analysis was developed to map a QTL within a marker brackett and to simultaneously predict QTL effects and estimate QTL, additive genetic, and residual variances. The analysis was applied to a simulated granddaughter design typical for dairy cattle.

F. E Grignola, I. Hoeschele, K. Meyer

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 245–248, 1994
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