The appropriateness of casein alleles assembled in haplotypes as genetics markers is studied. Polymorphic Information Content (PIC) of casein haplotypes (.78) is substantially higher than PIC of individual casein loci (ranging from .16 to .50) in Norwegian Cattle. Preliminary results show that haplotype 5 (with allele C of crs1-CN) is significantly associated with high protein yield, protein percentage and milk yield. Haplotypes 7, 8, and 9 (with allele B of k-CN) showed no significant associations with milk production traits. These results are compared to other studies in a literature review. The use of haplotype information in the genetic improvement of Norwegian Cattle is discussed. 

S. Lien, Gomez L. Raya

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 19. Selection and quantitative genetics; growth; reproduction; lactation; fish; fiber; meat., , 323–326, 1994
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