Abstract

The objective of this study was to identify quantitative trait loci underlying the genetic variation of milk production in an elite dairy cattle population. A total of 1518 progeny- tested sires, belonging to 14 paternal half-sib families, were genotyped with 159 autosomal microsatellites composing a marker map bracketing 1645 centimorgan or approximately two thirds of the bovine genome. Using multilocus linkage analysis, five chromosomes gave very strong evidence (lodscore > 3) for the presence of a quantitative trait locus: chromosomes 1, 6, 9, 10 and 20. These findings demonstrate that loci with considerable effects on milk production are still segregating in highly selected populations and pave the way towards marker assisted selection in dairy cattle breeding.
 

M. Georges, D. Nielsen, M. Mackinnon, A. Mishra, R. Okimoto, A. T Pasquino, L. S Sargeant, A. Sorensen, M. R Steele, X. Zhao, J. E Womack, I. Hoeschele

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 81–85, 1994
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