Abstract

Understanding the biochemical and physiological mechanisms underlying growth is one of the major subjects of interest in the cattle industry. Several studies have investigated the growth factors and growth hormones that influence growth. However, it is still unclear which genes and how many genes are involved in the process of growth. Calpastatin, which is an endogenous protease inhibitor (EC 3.4.22.17, Ca2+ dependent cysteine proteinase), has been studied (Goll et al., 1992), along with several growth factors, to investigate their effects on growth, and on cell growth and differentiation (Temm-Grove et al., 1999). Cottin et al. (1994) reported that the calpain system may influence cell growth. If the calpastatin system is highly heritable, and has moderate to high genetic correlations with economic traits of interest, its use in a selection program may increase the rate of genetic change. Carcass traits are often used to evaluate meat quality. Marbling is one of the major traits used in evaluation of meat quality (Wulf et al., 1996). Significant relationships among carcass traits, and between the calpain system and meat tenderness (Shackelford et al., 1994), have been reported. Carcass traits are influenced by genetic variations, and genetic differences in tenderness, marbling and calpastatin activity have been reported among and within breeds of cattle. Therefore, this study was carried out to investigate the effects of calpastatin genotypes on weight and carcass traits to provide genetic information for improvement of these traits.

H. Y Chung, C. D Kim, C. Y Cho, S. H Yeon, H. J Jin, K. J Jeon, H. C Kim, H. J Lee, H. C Hines, M. E Davis

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 2002. Session 11, , 11.33, 2002
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