Abstract

Acetylation/deacetylation of histones (chromosomal proteins) plays an important role in regulating gene transcription (Taunton et al., 1996) and is mediated largely by histone deacetylases (HDACs). HDACs regulate different cellular functions, such as chromatin structure, gene expression and cell cycle progression (Jepsen et al., 2000 ; McKinsey et al., 2000). Fatty acid binding proteins (FABPs) are involved in regulating lipid metabolism and transport in the cytoplasm. FABP 3 has been significantly associated with intramuscular fat percentage (IMF) and body weight, but not clearly with backfat (BF) in pigs (Gerbens et al., 1999 and 2000). The objectives of this study were to identify genetic polymorphisms in HDAC 1 and 3 and FABP 3 and 4 and to assess their associations with growth, carcass and meat quality traits in a resource population.

X. Ye, J. AB Robinson, Z. Jiang, A. MV Gibbins, John P Gibson

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 2002. Session 11, , 11.11, 2002
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