Modern techniques being used to unravel the genetic mechanisms governing variation in complex traits combine information on phenotypic traits, molecular markers, and gene expression. Such studies, generally referred to as genetical genomics, involve expensive and labor-intensive techniques and generate massive and multidimensional data sets. Consequently, careful experimental design and appropriate data analysis are critical for their success. In this presentation we will outline some issues related to the design and analysis of such studies. Current methods available in the literature will be reviewed, and some directions for future research will be discussed. An ongoing research project with a swine resource population being conducted at Michigan State University will be presented as well.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume , , 23.11, 2006
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