The objective of the current nutrigenomics study was (1) to identify major genes and model gene networks and regulatory pathways that control feed intake, nutrient retention, growth and carcass traits including abdominal fat, and (2) to test candidate genes for their association with traits of economic importance. The functions of genes differentially expressed between the two groups that differ in feed efficiency indicate that feed intake, growth and body fat have to be studied simultaneously. The study revealed genes in the IGF pathway especially insulin-like growth factor binding protein 5 (IGFBP5) and melanocortin 5 receptor (MC5R) gene are important candidate genes associated with feed efficiency and abdominal fat in meat-type chickens.

Samuel E Aggrey, A. P Sanglikar, W. Zhang, L. A Cogburn

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume , , 14.02, 2006
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