The Myogenin gene is a member of the MyoD gene family, regulator of the myogenesis that takes place during embryonic development. The objective of this study was to perform a phylogeny analysis of the Myogenin gene and its evolutionary history in species that have their sequencing data in the Genbank by comparing the ratio of nonsynonymous nucleotide substitution (Ka) by the ratio of synonymous substitutions (Ks). The species used in the analysis were Sus scrofa (swine), Bos Taurus, Ovis aries, Homo sapiens (humans), Mus musculus (mice), Rattus norvegicus (rats), Gallus gallus (chickens) and Meleagris gallopavo (turkeys). The phylogenetic trees were obtained by Maximum Likelihood and the Ks and Ka substitution rates were by the Parsimony method. The results showed that the gene probably suffered an adaptive evolution in the Ruminantia group after these species diverged from their common ancestor. In the other species, the gene seems to be evolving in a conservative way.

A. S Schierholt, S. EF Guimaraes, S. R Paiva, D. A Faria, P. S Lopes, L. CS Chaves

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume , , 22.66, 2006
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