Abstract

Metritis is an important uterine disease that negatively impacts cow health and profitability. Single nucleotide polymorphisms (SNPs) associated with metritis status and time-to-metritis detection were detected using information on approximately 600,000 SNPs from approximately 2100 dairy cows in 16 US herds. The SNPs were evaluated using logistic and survival analysis procedures. On average, metritis was detected on 30.4% of the cows at 6.8 days postpartum. Metritis status and days-to-metritis were associated (P-value < 0.0001) with 199 and 7 SNPs, respectively. Most of these SNPs were mapped to intergenic regions and within known genes. Information from these genetic variants can be applied in genomic selection programs to reduce the incidence of metritis and accelerate detection with the goal of improving the overall health of the herd and minimize costs. Keywords: logistic, survival analysis, SNP

B. R Southey, D Gonzalez-Pena, P. J Pinedo, J. EP Santos, G.M. Schuenemann, G. JM Rosa, R. Gilbert, R. Bicalho, R Chebel, K. Galvao, C. Seabury, J Fetrow, W. W Thatcher, S. L Rodriguez-Zas

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Electronic Poster Session - Biology - Reproduction 1, , 345, 2018
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