Abstract

The aim of this study was to identify single nucleotide polymorphism (SNP) markers associated with subclinical mastitis (SCM) in the Norwegian Red (NR) population. Alternative SCM traits were defined based on testday somatic cell count (SCC) records, using thresholds of 50, 100, 150, 200, 250, 300, 350, and 400 x103 cells/ml. Genome-Wide Association Study (GWAS) was performed for each trait. Genotype information of 35,605 SNP from 3,795 NR sires with daughter records for SCM and lactation mean somatic cell score (LSCS) were included. In total, 210 significant SNP were identified on chromosome-wide significance level, per trait the number ranged from 17 to 29. Chromosome 26 had the highest number of significant SNP for SCM. Some of the SNP were associated with several traits and other were unique for one or two traits. Four unique SNP were detected on chromosome 3, 9, 15, 22 for SCM50, two on 3 and 19 for SCM100, one on 21 and 12 for SCM150 and SCM200, respectively. Two unique SNP were detected for SCM350 on chromosome 26 and two for SCM400 on chromosome 26. LSCS had two unique SNP on chromosome 4 and 19. The LSCS trait had the highest number of common significant SNP with SCM50 (18) and lowest with SCM350 and SCM400 (5). Keywords: Genome-wide association study, Subclinical mastitis, Norwegian Red, Somatic Cell Count

Elena Kirsanova, Bjørg Heringstad, Anna Lewandowska-Sabat, Ingrid Olsaker

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Electronic Poster Session - Biology & Species - Bovine (dairy) 1, , 167, 2018
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